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Oral Cancer Stages: Survival Rates and Treatment Approaches

Oral cancer is a broad term for cancer that affects the inside of the mouth. These cancers are often categorized under the category of neck and head cancer. These types of cancers often begin in the tissues of the mouth and throat. These cancers often include the lips, tongue, gums, cheeks, hard and soft palates, and the floor of the mouth. Understanding the stages of oral cancer, its survival rates, and its available treatment options is crucial for effective treatment outcomes.
In this blog, we’ll discover more about the stages of oral cancer and its stage-wise survival rates, treatment approaches, and prevention.
What are the stages of Oral cancer?
Oral cancer is a type of cancer often classified using a staging system called the TNM system, which generally stands for Tumor, Node, and Metastasis. This grading system helps to determine how far the cancer has spread and its severity in people.
Stage 0 (Carcinoma in Situ)
In stage 0, the tumor is found to have small and typically 2 cm or less than 2 cm in size, these tumors have not spread to lymph nodes or other parts of the body.
Treatment: Surgical removal of the tumor or laser therapy is usually performed to remove the abnormal cells before they can invade the deeper tissues.
Survival rates: The survival rate for stage 0 for oral cancer is nearly 100%, as it is localized and it can effectively be treated with minimal medical intervention.
Stage I:
In stage I, the tumor is small, typically 2 cm or less in size, and it has not spread to lymph nodes or other parts of the body.
Treatments: The surgical removal of the tumor, usually followed by radiation therapy to ensure complete removal of cancerous cells.
Survival rates: The five year survival rate for stage I cancer is approximately 85-99%.
Stage II
In stage II, the tumor grows larger, the size ranges between 2 and 4 cm, but it's still confined to the breast area where it has started and has not spread to lymph nodes or distant parts of the body.
Treatment: There are treatment options, including surgery, radiation, or a combination of both treatments. In some cases, chemotherapy may also be considered depending on the tumor’s location and type.
Survival rates: The survival rate for Stage II is approximately around 70%, as the cancer is still localized but larger than Stage I.
Stage III
The tumor in stage III may be larger than 4 cm or have spread to a lymph node nearby but not distant organs.
Treatment: The treatment is more aggressive and might involve surgery to remove the tumor, followed by chemotherapy and radiation. The doctor might also recommend targeted therapy if the cancer has specific molecular characteristics.
Survival rates: Many studies have suggested that the five-year survival rate for Stage III oral cancer ranges from 50 to 60%, depending on the tumor’s response to treatment and whether there are other complicating factors.
Stage IV
Stage IV oral cancer is known as the most advanced stage, where the cancer has spread to surrounding tissues like lymph nodes, or other distant organs including lungs and liver.
Treatments: The treatment at this stage is often considered complex. It might involve a combination of treatments, which include surgery, radiation therapy, chemotherapy, and immunotherapy. The main goal is to get palliative, or achieve remission and focusing on controlling the cancer and improving quality of life.
Survival rates: The average survival rate of Stage IV oral cancer is generally around 30-40%, in some cases, it can be less than this. It can vary widely depending on the extent of cancer metastasis, patient’s overall physical health, and their response to treatment.
Treatment approaches for Oral Cancer
The treatment options for these cancers generally vary based on the patient’s cancer stage, the location of the tumor, and the patient’s individual health conditions.
Here’s some of the treatments used for the cure of oral cancer, including:
- Surgery: The main goal of performing surgery is to completely remove the tumors. In its early stages, performing an oral surgery alone may be enough to treat these types of cancers. In more advanced stages, a more extensive surgery might be needed to remove these affected tissues, lymph nodes, and surrounding structures.
Challenges: After surgery, some patients might face functional issues like difficulty speaking, swallowing, or breathing, depending on the area of the throat or throat affected.
- Radiation therapy: Radiation therapy uses high- energy beams to destroy cancer cells, these treatments often used in combination with surgery to treat the remaining cancer cells or to shrink tumors before surgery.
Side effects: These treatments have side effects that can include dry mouth, difficulty swallowing, and skin irritation in the treatment site.
- Chemotherapy: These treatments use drugs that are effective in stopping cancer cells from growing. It is often used in advanced cancer treatments in combination with radiation therapy to enhance the treatment effects.
Side effects: Performing chemotherapy in people can cause nausea, hair loss, fatigue and weakened immune system.
- Targeted therapy: Targeted therapy uses drugs that specifically target cancer cells with minimal effect on normal and healthy cells. These treatments are usually used in combination with other treatments for advanced cancer stages.
For example: Drugs like cetuximab used to target proteins that cancer cells used to grow.
- Immunotherapy: Immunotherapy is an effective cancer treatment, and it is often used to help the immune system to recognize and destroy cancer cells. While performing immunotherapy is considered an emerging field in treating oral cancers, it has shown hope for patients with advanced stages.
For example: Immune checkpoint inhibitors like pembrolizumab used to treat advanced stage oral cancers.
How to prevent developing oral cancer in people?
Many studies have suggested that oral cancer can be prevented, and it can play a crucial role in preventing these cancers.
Here’s how you can prevent these types of cancer with the following tips. Including:
- If you are someone who likes to smoke tobacco, chew tobacco or use a water pipe, or vape, while cutting these habits can reduce your chances of developing these cancers.
- If you are someone who drinks alcohol excessively, then stop or limit the consumption of alcohol, as it will reduce the risk of cancer development.
- If you are generally exposed to sun and outside, then consider using sunscreen creams and lotions, UV-AB blocking sunscreen of your face and other exposed areas of your body.
- Get timely cancer prevention vaccines, such as HPV vaccine and Hepatitis B vaccines.
- Try to follow a healthy, balanced diet.
- If you are facing any issues in your teeth, then consider getting routine dental checkups. People between the ages of 20 and 40 should get a routine dental checkup every three years and get an annual examination above the age of 40.
Consult Today
Oral cancer is a complex and serious health condition but is often treatable and manageable when detected in the early stages. Understanding oral cancer stages and their survival rates often helps people to make more informed decisions about their health. People can identify oral cancers through early detection by performing regular screenings, avoiding tobacco and excessive alcohol consumption, and maintaining a healthy lifestyle. These are key to preventing these cancers in high-risk people.
At Oncare, we offer premium-quality cancer treatments, including advanced cancer surgeries at affordable price ranges with an experienced cancer specialist consultations.
If you or any loved ones of yours are diagnosed with cancer, then visit Oncare Cancer Center and book an appointment with our cancer specialist today. Get an estimated cost of your cancer treatments today!
Frequently Asked Questions
Oral cancers have several signs and symptoms that often be mistaken as common problems happening in the mouth. For example, if you notice any kinds of patches develop inside your mouth that can’t scrape away. Studies have shown that these patches are precancerous conditions.
These may include:
- Leukoplakia
- Erythroplakia
- Erythroleukoplakia
Here are some oral cancer tests performed to diagnose these cancers in suspected patients, including:
- Physical examination
- Brush biopsy or (scrape biopsy & exfoliative cytology)
- Incisional biopsy
- Indirect laryngoscopy & Pharyngoscopy
- Direct pharyngscopy & laryngoscopy
Here are the most common surgeries used for oral cancer, including:
- Primary tumor surgery
- Mandibulectomy
- Maxillectomy
- Sentinel lymph node biopsy
- Neck dissection
- Reconstruction
Here are some treatment options available for oral cancer, these may include:
- Radiation therapy
- Targeted therapy
- Chemotherapy
- Immunotherapy
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